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We employed a measurement tool to assess systematic reviews (AMSTAR-2) to evaluate the methodological rigor of the included systematic reviews (SRs), synthesized the GRADE results as reported, and conducted a narrative synthesis

The researchers used statistical techniques to account for differences that might occur with changes in treatment over time, and also to account for differences in the timing of when patients quit or resumed smoking

Differences in historical smoking rates, cultural norms and socioeconomic deprivation are more likely explanations

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